61365-95-5Relevant academic research and scientific papers
An improved protocol for the synthesis of 3,4-disubstituted isoxazol-5(4H)-ones through L-valine-mediated domino three-component strategy
Ahuja, Monika,Kour, Parteek,Kumar, Anil,Kumar, Ashok,Sharma, Pratibha
, (2020/08/19)
Abstract: An expeditious, metal-free protocol has been demonstrated for the synthesis of isoxazolone derivatives using domino multi-component strategy. The envisaged methodology involves the L-valine promoted three-component cyclo-condensation reaction of
Cu/TCH-pr&at;SBA-15 nano-composite: A new organometallic catalyst for facile three-component synthesis of 4-arylidene-isoxazolidinones
Dadras, Akbar,Kalhor, Mehdi,Sajjadi, Seyed Mehdi
, p. 27439 - 27446 (2020/08/17)
A copper complex supported on SBA-15 nanoparticles (Cu/TCH-pr&at;SBA-15) was synthesized by the post-synthesis modification of nano-mesoporous silica with 3-chloropropyltriethoxysilane (CPTES) and thiocarbohydrazide (TCH) and subsequent metal-ligand coord
Synthesis and characterization of nanocrystalline hydroxyapatite and its catalytic behavior towards synthesis of 3,4-disubstituted isoxazole-5(4H)-ones in water
Maleki, Behrooz,Chahkandi, Mohammad,Tayebee, Reza,Kahrobaei, Sepideh,Alinezhad, Heshmatollah,Hemmati, Saba
, (2019/08/02)
In the present work, the nanocrystalline particles of hydroxyapatite (HAp) using an easy alkoxide-based sol–gel technique including triethyl phosphate [PO (OC2H5)3] and Ca (NO3)2·4H2O as P and Ca precursors have been synthesized. The sample characterization was performed by X-ray diffraction, Fourier transform-infrared analysis, scanning electron microscopy, thermal analysis (thermogravimetric analysis/differential thermal analysis), and elemental analysis of energy-dispersive X-ray analysis. It is interesting that single phase of HAp was obtained at a low firing temperature of 500°C. Modified Scherrer equation as the Williamson?Hall method was applied for the measurement of crystallite size distributions and micro-strain of the sample. The determined crystallite size by complementary technique of transmission electron microscopy has good consistency with those obtained from the Scherrer formula. Moreover, we reported the one-pot synthesis of 3,4-disubstituted isoxazole-5(4H)-ones through the aqueous solution reaction of three components of ethyl acetoacetate, hydroxylamine hydrochloride and various aromatic aldehydes at room temperature. This protocol offers several advantages, including a simple work-up procedure, very short reaction times (under 25?min), in accordance with the principles of green chemistry, recyclability, excellent yields (87–98%) and environmentally friendly.
A green and efficient synthesis of isoxazol-5(4H)-one derivatives in water and a DFT study
Pourmousavi, Seied Ali,Fattahi, Hamid Reza,Ghorbani, Fatemeh,Kanaani, Ayoub,Ajloo, Davood
, p. 455 - 469 (2018/03/29)
A series of 4-arylmethylene-3-methylisoxazol-5(4H)-one derivatives are obtained via treating ethyl acetoacetate, hydroxylamine hydrochloride and variety of aromatic aldehyde compounds in the presence of antimony trichloride as an efficient catalyst in aqu
A novel dicationic ionic liquid as a highly effectual and dual-functional catalyst for the synthesis of 3-methyl-4-arylmethylene-isoxazole-5(4H)-ones
Irannejad-Gheshlaghchaei, Navid,Zare, Abdolkarim,Sajadikhah, Seyed Sajad,Banaei, Alireza
, p. 6253 - 6266 (2018/06/04)
Abstract: A novel dicationic ionic liquid, N,N,N′,N′-tetramethyl-N,N′-bis(sulfo)ethane-1,2-diaminium mesylate [TMBSED][OMs]2), has been produced, and identified by analysis of its 1H NMR, 13C NMR, FT-IR, mass and thermal g
New eco-friendly procedure for the synthesis of 4-arylmethylene-isoxazol-5(4H)-ones catalyzed by pyridinium p-toluenesulfonate (PPTS) in aqueous medium
Laroum, Rima,Debache, Abdelmadjid
, p. 1876 - 1882 (2018/06/25)
In this work we describe a new, highly efficient method for the synthesis of 3-methyl-4-arylmethylidene-isoxazol-5(4H)-one derivatives by a three-component reaction between aromatic aldehydes, ethyl acetoacetate, and hydroxylamine hydrochloride under the
Sonochemical synthesis of 3-methyl-4-arylmethylene isoxazole-5(4H)-ones by amine-modified montmorillonite nanoclay
Safari, Javad,Ahmadzadeh, Majid,Zarnegar, Zohre
, p. 91 - 95 (2016/08/23)
Ultrasound irradiation was applied for the rapid and clean synthesis of 3-methyl-4-arylmethylene isoxazole-5(4H)-ones through condensation of hydroxylamine hydrochloride, ethyl acetoacetate and benzaldehyde derivatives. This methodology was effectively ca
One-pot green synthesis of isoxazol-5(4H)-one derivatives using Dowex1-x8OH in water
Setamdideh, Davood
, p. 971 - 978 (2016/11/09)
4-(Arylmethylidene)-3-methylisoxazol-5(4H)-ones and 4-(arylmethylidene)-3-phenylisoxazol-5(4H)-ones were synthesized in a one-pot three-component procedure in the presence of Dowex1-x8OH as catalyst in water. The products were obtained in high yields (90-
