61367-13-3 Usage
Uses
Used in Pharmaceutical Industry:
(4-[(2-fluoroethyl)carbamoyl]aminocyclohexyl)methyl acetate is used as a building block for the synthesis of various bioactive molecules, leveraging its carbamoyl and amino groups for potential medicinal applications.
Used in Agrochemical Industry:
In the agrochemical sector, (4-[(2-fluoroethyl)carbamoyl]aminocyclohexyl)methyl acetate is used as a precursor for the development of novel compounds with pesticidal or herbicidal properties, taking advantage of its unique structural features to target specific pests or weeds.
Used in Chemical Research:
(4-[(2-fluoroethyl)carbamoyl]aminocyclohexyl)methyl acetate serves as a subject of study in chemical research, where its reactivity, stability, and interaction with other molecules are investigated. The fluorinated ethyl group may provide insights into the effects of fluorination on molecular properties and reactivity.
Used in Drug Design:
(4-[(2-fluoroethyl)carbamoyl]aminocyclohexyl)methyl acetate is utilized in drug design for the creation of new pharmaceutical agents, possibly targeting specific receptors or enzymes due to its diverse functional groups and structural complexity.
Overall, the compound (4-[(2-fluoroethyl)carbamoyl]aminocyclohexyl)methyl acetate holds promise in various applications across different industries, primarily due to its unique structural composition and the potential bioactivity conferred by its functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 61367-13-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,6 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 61367-13:
(7*6)+(6*1)+(5*3)+(4*6)+(3*7)+(2*1)+(1*3)=113
113 % 10 = 3
So 61367-13-3 is a valid CAS Registry Number.
61367-13-3Relevant academic research and scientific papers
Synthesis of analogues of N (2 chloroethyl) N' trans 4 methylcyclohexyl) N nitrosourea for evaluation as anticancer agents
Johnston,McCaleb,Clayton,Frye,Krauth,Montgomery
, p. 279 - 290 (2007/10/04)
The superior activity of N (2 chloroethyl) N' (trans 4 methylcyclohexyl) N nitrosourea (MeCCNU) against advanced murine Lewis lung carcinoma in comparisons with the cis form and other nitrosoureas prompted the synthesis of a number of MeCCNU analogues, including several cis trans pairs. The methyl group was replaced by a variety of substituents (CO2H, CH2CO2H, CO2Me, CH2OAc, CH2Cl, OMe); the trans 3 methylcyclohexyl, cis 2 methyl 1,3 dithian 5 yl, cis and trans 2 methyl 1,3 dithian 5 yl tetraoxide, and 1 methylhexyl (open chain) analogues were also prepared. Preliminary tests against murine leukemia L1210 revealed therapeutic indices (ED50/LD10) ranging from 0.26 to 0.79; all but 3 analogues effected 50% cure rates at nontoxic doses, the open chain analogue being one of the least active. In terms of therapeutic index, diequatorial (trans 4) isomers were, with one exception, as active as or, in 4 of the 8 examples, somewhat more active than the corresponding axial equatorial (cis 4) isomers. In this series, 4 of the 5 2-fluoroethyl analogues prepared were clearly inferior to the corresponding 2 chloroethyl analogues.
