613671-68-4

Upstream product

• 542-08-5 isopropyl acetoacetate 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 613671-74-2 1-benzyl-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-2,3,5-tricarboxylic acid 5-isopropyl ester 2,3-dimethyl ester 
• 613671-71-9 4-(2-chloro-phenyl)-1-ethyl-2-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-isopropyl ester 5-methyl ester 
• 613671-73-1 4-(2-chloro-phenyl)-6-methyl-1-(2,2,2-trifluoro-ethyl)-1,4-dihydro-pyridine-2,3,5-tricarboxylic acid 5-isopropyl ester 2,3-dimethyl ester 

Relevant academic research and scientific papers

Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors

The synthesis of a series of novel dihdyropyridine diacid glycogen phosphorylase inhibitors is presented. SAR and functional assay data are discussed, along with the effect of a single inhibitor on blood glucose in a diabetic animal model.