613681-75-7Relevant academic research and scientific papers
A new Co(0) complex mediated synthesis of C-glycoside analogues
Orsini, Fulvia,Di Teodoro, Emanuela
, p. 2521 - 2528 (2003)
Properly protected glyconolactones, readily available from the parent sugars, react under mild conditions with α-bromoacetates in the presence of a soluble Co(0) complex, either in stoichiometric or substoichiometric amounts, to give a Reformatsky-type addition product to the lactone. The addition product can be subsequently converted into a variety of compounds: dehydroxylation with triethylsilane in the presence of boron trifluoride affords C-glycosides.
