61380-88-9Relevant academic research and scientific papers
Synthesis of substituted 2H-benzo[e]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3β pathways
Taneja, Gaurav,Gupta, Chandra Prakash,Mishra, Shachi,Srivastava, Rohit,Rahuja, Neha,Rawat, Arun Kumar,Pandey, Jyotsana,Gupta, Anand P.,Jaiswal, Natasha,Gayen, Jiaur R.,Tamrakar, Akhilesh K.,Srivastava, Arvind Kumar,Goel, Atul
, p. 329 - 337 (2017/03/08)
Based on high throughput screening of our chemical library, we identified two 4,5-dihydro-2H-benzo[e]indazole derivatives (5d and 5g), which displayed a significant effect on glucose uptake in L6 skeletal muscle cells. Based on these lead molecules, a ser
Reaction of 6-aryl- or styryl-4-methylsulfanyl-2-oxo-2H-pyrans with active methylene compounds and fluorescence properties of the products
Mizuyama, Naoko,Murakami, Yuka,Nakatani, Takatoshi,Kuronita, Keiko,Kohra, Shinya,Ueda, Kazuo,Hiraoka, Kyoko,Tominaga, Yoshinori
, p. 265 - 277 (2008/09/19)
(Chemical Equation Presented)New 2-pyrone derivatives, dialkyl 3-cyano-6-phenyl-2-oxo-2H-pyran-4-ylmalonates and alkyl 3-cyano-6-phenyl-2-oxo- 2H-pyran-4-ylacetates, which were easily prepared by the reaction of 6-aryl-4-methyl-sulfanyl-2-oxo-2H-pyran-3-c
Synthesis and fluorescence of 2H-pyrone derivatives for organic light-emitting diodes (OLED)
Mizuyama, Naoko,Murakami, Yuka,Kohra, Shinya,Ueda, Kazuo,Hiraoka, Kyoko,Nagaoka, Junko,Takahashi, Kojiro,Shigemitsu, Yasuhiro,Tominaga, Yoshinori
, p. 115 - 132 (2008/09/16)
(Chemical Equation Presented) 2H-Pyrone derivatives were synthesized through the reaction of aryl acetyl compounds with ketene dithioacetals in the presence of sodium hydroxide, and they showed very strong fluorescence in the solid state. The light-emitti
A novel synthesis of aryl tethered imidazo[4,5-b]pyrazin-2-ones through in situ ring construction and contraction
Pratap, Ramendra,Roy, Abhijeet Deb,Roy, Raja,Ram, Vishnu Ji
, p. 1281 - 1285 (2007/10/03)
An innovative synthesis of aryl tethered 1,3-dimethylimidazo[4,5-b]pyrazin-2-ones 4 and 6 has been delineated through base catalyzed ring transformation of 6-aryl-4-(piperidin-1-yl)-2H-pyran-2-one-3-carbonitriles 1 and methyl 6-aryl-4-methylsulfanyl-2H-py
Substituent directed regioselective synthesis of 2-oxonicotonic acids and methyl nicotinates
Pratap, Ramendra,Farahanullah,Raghunandan, Resmi,Maulik,Ram, Vishnu Ji
, p. 4939 - 4942 (2008/02/08)
An innovative synthesis of aryl tethered 1,2-dihydro-2-oxopyridine-3-carboxylic acids has been developed through nucleophile induced ring transformation of methyl 6-aryl-4-methylsulfanyl-2H-pyran-2-one-3-carboxylates using either cyanamide or arylamidine
Acetyltrimethylsilane: A novel reagent for the transformation of 2H-pyran-2-ones to unsymmetrical biaryls
Goel, Atul,Verma, Deepti,Dixit, Manish,Raghunandan, Resmi,Maulik
, p. 804 - 807 (2007/10/03)
An expeditious synthesis of unsymmetrical biaryls functionalized with electron-withdrawing or -donating substituents is described and illustrated by carbanion-induced ring transformation of 2H-pyran-2-one using acetyltrimethylsilane (ATMS) as a novel reag
Synthesis and Reaction of 6-Substituted 3-Methoxycarbonyl-4-methylthio-2H-pyran-2-one Derivatives
Tominaga, Yoshinori,Ushirogochi, Atsuyuki,Matsuda, Yoshiro
, p. 1557 - 1567 (2007/10/02)
Reaction of aryl and styryl methyl ketones 1a-m with dimethyl bis(methylthio)methylenemalonate (2) in the presence of potassium hydroxide in dimethyl sulfoxide gave the corresponding methyl 6-aryl- and 6-styryl-4-methylthio-2-oxo-2H-pyran-3-carboxylates 3
