61404-52-2

Usage

Uses

Used in Pharmaceutical Industry:
2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid is used as an intermediate in the synthesis of various pharmaceuticals for its potential pharmacological properties. Its chemical structure allows for versatile chemical interactions and reactivity, making it a promising candidate for the development of new drugs.
Used in Organic Synthesis:
2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid is used as a building block in the production of other organic compounds due to its unique structure and functional groups. This makes it a valuable component in the synthesis of a wide range of organic molecules for various applications.
Used in Antioxidant and Anti-inflammatory Applications:
2-oxo-3-(3,4,5-trimethoxyphenyl)propanoic acid is used as an antioxidant and anti-inflammatory agent for its potential pharmacological properties. Its ability to combat oxidative stress and reduce inflammation may contribute to the development of treatments for various diseases and conditions.

InChI:InChI=1/C12H14O6/c1-16-9-5-7(4-8(13)12(14)15)6-10(17-2)11(9)18-3/h5-6H,4H2,1-3H3,(H,14,15)

Upstream product

• 62616-09-5 2-Phenyl-4-(3',4',5'-trimethoxybenzylidene)oxazolone 
• 100389-03-5 1-chloro-3-(3,4,5-trimethoxy-phenyl)-acetone 
• 1916-07-0 3,4,5-trimethoxybenzoic acid methyl ester 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 102373-86-4 2-(4-dimethylamino-phenylimino)-3-oxo-4-(3,4,5-trimethoxy-phenyl)-butyronitrile 

Downstream Products

• 108536-98-7 6-methoxy-3-((Ξ)-3,4,5-trimethoxy-benzylidene)-3H-benzofuran-2-one 
• 102159-53-5 4,6-dimethoxy-3-((Ξ)-3,4,5-trimethoxy-benzylidene)-3H-benzofuran-2-one 
• 951-82-6 3,4,5-trimethoxyphenyl acetic acid 
• 139109-56-1 Oxime of 3,4,5-trimethoxyphenylpyruvic acid 
• 73554-61-7 1-(3,4,5-trimethoxy-benzyl)-2,3,4,9-tetrahydro-1H-β-carboline 
• 219783-09-2 3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-dicarboxylic acid 
• 219783-10-5 1-[2-(4-methoxy-phenyl)-ethyl]-3,4-bis-(3,4,5-trimethoxy-phenyl)-1H-pyrrole-2,5-dicarboxylic acid diamide 
• 220231-11-8 Z,Z-3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-biscarboxamide 
• 220231-09-4 E,Z-3,4-bis(3,4,5-trimethoxyphenyl)-1-<2-(4-methoxyphenyl)ethyl>pyrrole-2,5-biscarboxamide 
• 50901-33-2 2-Hydroxy-4,5-methylenedioxy-6-methoxyphenyl-3,4,5-trimethoxybenzyl ketone 
• 41743-73-1 3',4',5',5-tetramethoxy-6,7-methylenedioxyisoflavone 
• 13338-63-1 2-(3,4,5-trimethoxyphenyl)acetonitrile 
• 129207-78-9 2,4-Dihydroxy-6-methoxyphenyl-3,4,5-trimethoxybenzyl ketone 
• 129207-79-0 2,4,5-Trihydroxy-6-methoxyphenyl-3,4,5-trimethoxybenzyl ketone 

Relevant academic research and scientific papers

Potent, selective tetrahydro-β-carboline antagonists of the serotonin 2B (5HT(2B)) contractile receptor in the rat stomach fundus

A series of potent, selective 5HT(2B) receptor antagonists has been identified based upon yohimbine, with SAR studies resulting in a 1000-fold increase in 5HT(2B) receptor affinity relative to the starting structure (- log K(B)s > 10.0 have been obtained). These high-affinity tetrahydro-β- carboline antagonists are able to discriminate among the 5HT2 family of serotonin receptors, with members of the series showing selectivities of more than 100-fold versus both the 5HT(2A) and 5HT(2C) receptors based upon radioligand binding and functional assays. As the first compounds reported with such selectivity and enhanced receptor affinity, these tetrahydro-β- carboline antagonists are useful tools for elucidating the role of serotonin acting at the 5HT(2B) receptor in normal and disease physiology.