61417-31-0Relevant academic research and scientific papers
Asymmetric Total Synthesis of (-)-Leuconoxine via Chiral Phosphoric Acid Catalyzed Desymmetrization of a Prochiral Diester
Higuchi, Kazuhiro,Suzuki, Shin,Ueda, Reeko,Oshima, Norifumi,Kobayashi, Emiko,Tayu, Masanori,Kawasaki, Tomomi
, p. 154 - 157 (2015/07/28)
The asymmetric total synthesis of (-)-leuconoxine has been achieved. The desymmetrization of a prochiral diester using a chiral phosphoric acid catalyst produced a highly enantioenriched lactam with excellent yield. The ring construction featuring an intr
