61425-05-6

Basic information

• Product Name: 1-hexopyranosyl-1H-imidazole
• CAS NO: 61425-05-6
• Molecular Formula: C₉H₁₄N₂O₅
• Molecular Weight: 230.2179
• Mol File: 61425-05-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 571.6°C at 760 mmHg
• Flash Point: 299.5°C
• Density: 1.74g/cm³
• Vapor Pressure: 6.63E-14mmHg at 25°C
• Refractive Index: 1.697
• CAS DataBase Reference: 1-hexopyranosyl-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-hexopyranosyl-1H-imidazole(61425-05-6)
• EPA Substance Registry System: 1-hexopyranosyl-1H-imidazole(61425-05-6)

Safety Data

• Hazardous Substances Data: 61425-05-6(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 61425-05-6 differently. You can refer to the following data:
1. The chemical compound is named based on its structure, which includes a hexopyranosyl group and an imidazole ring.
2. This name highlights the specific components of the compound, with "N" denoting the nitrogen atom and "D-glucopyranosyl" referring to the sugar component.
3. The compound consists of a six-membered sugar ring (hexopyranosyl) connected to a five-membered imidazole ring.
4. 1-hexopyranosyl-1H-imidazole is commonly used as a building block in the creation of complex carbohydrate-based molecules, such as glycoconjugates and glycopeptides.
5. The compound has potential applications in medicine due to its ability to target and interact with biological molecules, making it a candidate for treating various diseases.
6. The presence of the hexopyranosyl group makes the compound an important constituent in the field of carbohydrate chemistry, as it can be used to create more complex carbohydrate structures.
7. The imidazole ring in the compound is responsible for its potential biological activity, allowing it to interact with biological molecules and processes.

Structure

Hexopyranosyl group attached to an imidazole ring

Usage

Synthesis of glycoconjugates and glycopeptides

Therapeutic Implications

Treatment of diseases like cancer and fungal infections

Importance in Carbohydrate Chemistry

Hexopyranosyl group as a building block

Biological Activity

Imidazole ring contribution

Upstream product

• 572-09-8 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 
• 38953-70-7 1‐(2,3,4,6‐tetra‐O‐acetyl‐β‐D‐glucopyranosyl)imidazole 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 25484-69-9 N-(2,3,4,6-tetra-O-acetyl-D-glucopyranosyl)imidazole 

Relevant articles and documents

Proton-acceptor properties and capability for mutarotation of some glucosylamines in methanol

N-(m-Nitrophenyl)-β-D-glucopyranosylamine (Gln), N-(N-methylphenyl)- β-D-glucopyranosylamine (Glm), N-β-D-glucopyranosylpyrazole (Glp), and N-β-D-glucopyranosylimidazole (Gli) have been synthesized. Their basicity constants, pKb, determined in methanol were, respectively, 14.99, 14.36, 15.04, and 9.74. The derivatives of secondary amines (Glm, Glp, and Gli) did not mutarotate in methanol in the presence of 3,5-dinitrobenzoic acid and hydrochloric acid. The heats of formation and entropies were calculated by the AM1 and PM3 methods for the glucosylamines and their cations under consideration of two plausible protonation centers. Thermodynamic parameters for the proton transfer in the reaction: glucosylamine+CH3OH2 +=glucosylamineH++CH3OH were determined and the protonation center in the glucosylamine molecule was identified. The mechanism of mutarotation of the glucosylamines is discussed and the conclusion made that formation of an acyclic immonium cation is not a satisfactory condition for the reaction to proceed.

Absence of reverse anomeric effect: Conformational analysis of glucosylimidazolium and glucosylimidazole

-