61441-65-4 Usage
General Description
The chemical [(2S,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol, also known as clotrimazole, is an antifungal medication used to treat a variety of fungal infections in the body. It works by inhibiting the growth of fungi and is commonly used to treat infections such as athlete's foot, ringworm, jock itch, and yeast infections. Clotrimazole is available in various forms including creams, powders, and topical solutions for external use, as well as oral lozenges for oral thrush. It is generally well tolerated with few side effects, making it a commonly used and effective antifungal agent.
Check Digit Verification of cas no
The CAS Registry Mumber 61441-65-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,4,4 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61441-65:
(7*6)+(6*1)+(5*4)+(4*4)+(3*1)+(2*6)+(1*5)=104
104 % 10 = 4
So 61441-65-4 is a valid CAS Registry Number.
61441-65-4Relevant articles and documents
Synthesis, antifungal activity and structure-activity relationships of 2-(alkyl or aryl)-2-(alkyl or polyazol-1-ylmethyl)-4-(polyazol-1-ylmethyl)- 1,3-dioxolanes
Baji,Kimny, Tan,Gasquez,Flammang,Compagnon,Delcourt,Mathieu,Viossat,Morgant,Nguyen-Huy
, p. 637 - 650 (2007/10/03)
A series of 2-(alkyl or aryl)-2-(alkyl or polyazol-1-ylmethyl)-4-(polyazol-1-ylmethyl)-1,3-dioxolanes Ia-u was synthesized and tested in vitro against pathogenic fungi in man, animals and plants: Candida albicans, Aspergillus flavus and Fusarium solani. Compounds Iq-t with two polyazol groups have an in vitro activity against these fungi with MIC (minimum inhibitory concentration) value of 5 μg mL-1.
