61445-55-4Relevant academic research and scientific papers
Structural effects on the n-nitrosation of amino acids
Gil, Rafael,Casado, Julio,Izquierdo, Carmen
, p. 495 - 504 (1997)
The relative importance of three different routes for the N-nitrosation of amino acids (nitrosation by N2O3, by NO+/NO2H2+ and by intramolecular migration of the nitroso group from the init
Synthesis method of N-nitroso-N-methyl-4-aminobutyric acid
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Paragraph 0008; 0029; 0031-0032; 0034-0035; 0037, (2020/12/30)
The invention discloses a synthesis method of N-nitroso-N-methyl-4-aminobutyric acid, which comprises the following steps: carrying out alkali ring opening and hydrolysis on N-methyl pyrrolidone as shown in a formula I to form a compound as shown in a formula II, and reacting the compound as shown in the formula II with a nitrite to obtain a product as shown in a formula III. The method disclosedby the invention is simple in process route, simple and convenient to operate and mild in reaction condition, the target product N-nitroso-N-methyl-4-aminobutyric acid is obtained through two-step organic synthesis, and HNMR result shows that no impure peak exists.
