61448-82-6Relevant academic research and scientific papers
COMPOUNDS FOR TREATING INFLAMMATORY AND HYPERPROLIFERATIVE DISEASES
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Paragraph 00116, (2014/10/15)
Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.
2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: Novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays
Costi, Roberta,Di Santo, Roberto,Artico, Marino,Massa, Silvio,Ragno, Rino,Loddo, Roberta,La Colla, Massimiliano,Tramontano, Enzo,La Colla, Paolo,Pani, Alessandra
, p. 199 - 215 (2007/10/03)
A number of 2,6-bisbenzylidenecyclohexane-1-one derivatives have been synthesized and tested as HIV-1 integrase (IN) inhibitors with the aim of obtaining compounds capable to elicit antiviral activity at non-cytotoxic concentrations in cell-based assays.
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues
Rovnyak,Millonig,Schwartz,Shu
, p. 1482 - 1488 (2007/10/02)
A series of novel hexahydrothiopyrano[4,3-c]pyrazoles and related analogues were prepared and tested for antiinflammatory activity by using the mouse active Arthus reaction and the delayed hypersensitivity skin reaction in guinea pigs as primary screens.
Substituted pyrano[4,3-c]pyrazoles, compositions containing same, and method of use
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, (2008/06/13)
2,4,6,7-Tetrahydropyrano[4,3-c]pyrazoles are provided having the formula STR1 wherein Z is O, S, SO or SO2 ; R is H, halo, lower alkyl, lower alkoxy, lower alkanoyl, aroyl, cyano or CF3 ; and R' is H, lower alkyl, aryl-lower alkyl, a
