6145-29-5

Usage

Uses

Used in Water Treatment Industry:
Sodium methylenediphosphonate is used as a corrosion and scale inhibitor in cooling water systems for preventing the buildup of scale and corrosion on equipment surfaces, thereby enhancing the efficiency and longevity of the systems.
Used in Detergent Production:
In the detergent industry, sodium methylenediphosphonate is used as a builder to enhance the cleaning efficiency of detergents by sequestering metal ions and preventing the formation of insoluble salts.
Used in Oil and Gas Industry:
Sodium methylenediphosphonate is utilized in the oil and gas industry as a corrosion inhibitor in drilling fluids and as a scale inhibitor in oilfield operations, ensuring smooth and efficient extraction processes.
Used in Textile Industry:
In the textile industry, sodium methylenediphosphonate is used as a stabilizer to prevent the degradation of dyes and enhance the colorfastness of fabrics during washing and other processes.
Used in Paper Industry:
Sodium methylenediphosphonate is employed in the paper industry as a stabilizer to prevent the discoloration and degradation of paper products, ensuring their quality and longevity.
Sodium methylenediphosphonate is considered environmentally friendly and has low acute toxicity, making it a popular choice in various industrial applications.

Upstream product

• 2857-97-8 trimethylsilyl bromide 
• 1660-94-2 Tetraethyl methylenediphosphonate 
• 1660-95-3 Tetraisopropyl methylenediphosphonate 

Downstream Products

• 59-56-3 α-D-glucopyranosyl-1-phosphate 

Relevant academic research and scientific papers

Design, synthesis and activity of bisubstrate, transition-state analogues and competitive inhibitors of aspartate transcarbamylase

Aspartate transcarbamylase initiates the de novo biosynthetic pathway for the production of the pyrimidine nucleotides, precursors of nucleic acids. This pathway is particularly active in rapidly growing cells and tissues. Thus, this enzyme has been tested as a potential target for antiproliferative drugs. In the present work, on the basis of its structural and mechanistic properties, a series of substrate analogues, including potential suicide-pseudosubstrates was synthesized and their putative inhibitory effects were tested using E. coli aspartate transcarbamylase as a model. Two of these compounds appear to be very efficient inhibitors of this enzyme.

Synthesis and heteronuclear NMR analysis of deuterium- and tritium-labelled methylenebisphosphonic acid

Deuterium has been substituted into the methylene group of methylenebisphosphonic acid, MDP. Analysis of the phosphorus NMR spectrum of the product shows a linear high-frequency shift on sequential mono- and di-deuteriation. The corresponding tritium labelling of MDP achieved a specific activity of 30 mCi/mmol.

SYNTHESIS OF ALKYLATED METHYLENE BISPHOSPHONATES VIA ORGANOTHALLIUM INTERMEDIATES

Thallium(I) derivatives of esterified methylene bisphosphonates can be readily obtained by treating the latter with thallium(I) ethoxide under anhydrous conditions.Alkylation of the thallium(I) derivatives by a range of primary alkyl iodides takes place smoothly, and significantly higher yields are obtained than for the corresponding reactions with lithio or sodio derivatives.