61458-01-3

Basic information

• Product Name: 2-Azetidinone, 4-(4-methoxyphenyl)-1-(4-methylphenyl)-3-(phenylmethoxy)-, cis-
• CAS NO: 61458-01-3
• Molecular Formula: C24H23NO3
• Molecular Weight: 373.452
• Mol File: 61458-01-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Azetidinone, 4-(4-methoxyphenyl)-1-(4-methylphenyl)-3-(phenylmethoxy)-, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone, 4-(4-methoxyphenyl)-1-(4-methylphenyl)-3-(phenylmethoxy)-, cis-(61458-01-3)
• EPA Substance Registry System: 2-Azetidinone, 4-(4-methoxyphenyl)-1-(4-methylphenyl)-3-(phenylmethoxy)-, cis-(61458-01-3)

Safety Data

• Hazardous Substances Data: 61458-01-3(Hazardous Substances Data)

Upstream product

• 30379-55-6 benzyloxyacetic acid 
• 83306-66-5 N-(p-methoxybenzylidene)-p-toluidine 
• 3246-78-4 N-(4-methoxybenzylidene)-4-methylaniline 

Relevant articles and documents

Synthesis of β-lactams from acetic acids and imines induced by phenyl dichlorophosphate reagent

The development of a practical method for the preparation of vinylamino-β-lactams from Dane salts and Schiff bases is described. Among the reagents known to produce β-lactams from imines and acetic acids, only phenyl dichlorophosphate and 1-methyl-2-chloropyridinium iodide are suitable for the synthesis of vinylamino-β-lactams. Reaction of acetic acids with ethanolimine derivatives promoted by phenyl dichlorophosphate affords oxazolidines instead of β-lactams. Protection of the hydroxyl group as the trimethylsilyl ether in the starting Schiff bases provides a convenient route to the corresponding β-lactams instead of oxazolidines. Some observations on the scope of the method are made.

Synthesis of α-hydroxy-β-lactams

-