61458-06-8

Upstream product

• 6780-38-7 N-phthaloylglycine chloride 
• 40339-42-2 4-methoxy-N-[(1Z)-phenylmethylene]aniline 
• 4702-13-0 N-phthaloylglycine 
• 783-08-4 [4-(benzylideneamino)phenyl]methanol 

Downstream Products

• 82357-25-3 2-((3S,4R)-2-Oxo-4-phenyl-azetidin-3-yl)-isoindole-1,3-dione 

Relevant academic research and scientific papers

Novel synthesis of 3-pyrrole substituted β-lactams via microwave-induced bismuth nitrate-catalyzed reaction

Highly stereoselective synthesis of 3-pyrrole substituted β-lactams is accomplished. The first step involves the synthesis of 3-phthalimido substituted β-lactams following Staudinger cycloaddition reaction of acid chloride equivalent with imines. Synthesi

Acetoxylation of β-lactams with lead(IV) acetate

1-(4-Methoxyphenyl)azetidin-2-ones 5a-5g were acetoxylated by lead(IV) acetate to afford the corresponding compounds 6a, 6b, 6c' and 6d-6g. In the d series elimination products 9 and 10 were also formed. Ring homologue 7a afforded the hydroxylated derivat