614731-04-3 Usage
Uses
Used in Pharmaceutical Industry:
1-Boc-4-fluoro-4-piperidinecarboxylic acid serves as a key building block in organic synthesis, particularly for the development of pharmaceuticals. Its utility stems from the ability to modify the compound's reactivity and stability through the Boc protecting group, as well as the introduction of fluorine, which can improve the drug's pharmacokinetics, such as lipophilicity, metabolic stability, and bioavailability.
Used in Medicinal Chemistry Research:
As a fluorinated derivative, 1-Boc-4-fluoro-4-piperidinecarboxylic acid is utilized in medicinal chemistry for the design and synthesis of novel drug candidates. The presence of fluorine can fine-tune the molecule's binding affinity to biological targets, potentially leading to more effective therapeutic agents.
Used in Organic Synthesis:
1-Boc-4-fluoro-4-piperidinecarboxylic acid is employed as an intermediate in the synthesis of complex organic molecules. The Boc group can be selectively removed when needed, allowing for further functionalization of the molecule, which is crucial for the creation of diverse chemical libraries in drug discovery.
Used in Drug Discovery and Development:
1-Boc-4-fluoro-4-piperidinecarboxylic acid is instrumental in the drug discovery and development process, where its unique structural features can be leveraged to create new pharmaceutical entities. Its role as a versatile intermediate allows for the exploration of various chemical modifications, which can lead to the optimization of drug candidates for efficacy, safety, and other desirable pharmaceutical attributes.
Check Digit Verification of cas no
The CAS Registry Mumber 614731-04-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,4,7,3 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 614731-04:
(8*6)+(7*1)+(6*4)+(5*7)+(4*3)+(3*1)+(2*0)+(1*4)=133
133 % 10 = 3
So 614731-04-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H18FNO4/c1-10(2,3)17-9(16)13-6-4-11(12,5-7-13)8(14)15/h4-7H2,1-3H3,(H,14,15)
614731-04-3Relevant academic research and scientific papers
ARYLSULFONYL DERIVATIVES AND THEIR USE AS MUSCARINIC ACETYLCHOLINE RECEPTOR M5 INHIBITORS
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Paragraph 00278, (2022/01/04)
Arylsulfonamides of carboxamido-piperidines, -pyrrolidines, and -azetidines, and their derivatives, are competitive and non-competitive inhibitors of the muscarinic acetylcholine receptor M5 (mAChR M5) and have utility in the treatment of psychiatric disorders such as substance-related misuse, substance- related disorder relapse, anxiety, depression, and psychosis.
BENZOFURAN COMPOUNDS
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Page/Page column 32-33, (2008/12/08)
A compound of formula (I), wherein R1, R2, and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in
