614755-53-2Relevant academic research and scientific papers
An efficient total synthesis of 9-methoxycarbazole-3-carbaldehyde based on a novel methodology for the preparation of methoxyindoles
Selvakumar,Khera, Manoj Kumar,Reddy, B. Yadi,Srinivas,Azhagan, A. Malar,Iqbal, Javed
, p. 7071 - 7074 (2007/10/03)
A direct synthesis of naturally occurring 9-methoxycarbazole-3-carbaldehyde 1, based on our methodology for the synthesis of 1-methoxyindoles, is reported. A novel benzannulation strategy was employed using ring closing metathesis as the key step in this total synthesis. The synthesis of the natural product 1 has been achieved in seven steps in 14% overall yield from commercial materials and in only four steps from a methoxyindole compound obtained using the new methodology.
