61494-42-6

Basic information

• Product Name: N,2-dihydroxy-5-nitrobenzaMide
• Synonyms: N,2-dihydroxy-5-nitrobenzaMide
• CAS NO: 61494-42-6
• Molecular Formula: C₇H₆N₂O₅
• Molecular Weight: 198.13294
• Mol File: 61494-42-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.636±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.52±0.16(Predicted)
• CAS DataBase Reference: N,2-dihydroxy-5-nitrobenzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N,2-dihydroxy-5-nitrobenzaMide(61494-42-6)
• EPA Substance Registry System: N,2-dihydroxy-5-nitrobenzaMide(61494-42-6)

Safety Data

• Hazardous Substances Data: 61494-42-6(Hazardous Substances Data)

Usage

General Description

N,2-dihydroxy-5-nitrobenzamide is a chemical compound with the molecular formula C7H6N2O5. It is a nitrobenzamide derivative with two hydroxyl groups and a nitro group. N,2-dihydroxy-5-nitrobenzaMide is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various organic compounds and pharmaceuticals. It is also used as an intermediate in the synthesis of dyes and pigments. N,2-dihydroxy-5-nitrobenzamide has potential applications in the development of new drugs and medical treatments. However, it is important to handle and use this compound with care due to its potentially hazardous properties.

Upstream product

• 17302-46-4 methyl 2-hydroxy-5-nitrobenzoate 
• 96-97-9 5-nitrosalicylic acid 

Downstream Products

• 29050-07-5 2-(2-chloro-ethyl)-3-hydroxy-6-nitro-2,3-dihydro-benzo[e][1,3]oxazin-4-one 
• 36238-80-9 5-Nitro-3-hydroxy-1,2-benzisoxazol 
• 36238-80-9 5-nitro-1,2-benzoxazol-3-one 
• 16302-63-9 3-Chlor-5-nitro-1,2-benzisoxazol 

Relevant articles and documents

TETRAHYDROISOQUINOLINE DERIVATIVES

The present invention relates to tetrahydroisoquinoline derivatives according to formula (I), wherein G represents a fused heterocyclic system selected from the groups represented by formula (G1), (G2), (G3), (G4/sup

Benzohydroxamic acids as potent and selective anti-HCV agents

A diverse collection of 40 derivatives of benzohydroxamic acid (BHAs) of various structural groups were synthesized and tested against hepatitis C virus (HCV) in full-genome replicon assay. Some of these compounds demonstrated an exceptional activity, suppressing viral replication at sub-micromolar concentrations. The compounds were inactive against key viral enzymes NS3, and NS5B in vitro assays, suggesting host cell inhibition target(s). The testing results were consistent with metal coordination by the BHAs hydroxamic group in complex with a target(s). Remarkably, this class of compounds did not suppress poliomyelitis virus (PV) propagation in RD cells indicating a specific antiviral activity of BHAs against HCV.