61508-05-2Relevant articles and documents
Novel benzothienyl amino (propyl and butyl) ketones, a method of preparation thereof and their application to therapeutics
-
, (2008/06/13)
Compounds having the formula STR1 wherein R1 and R2 are alkyl having one to 4 carbon atoms, allyl or STR2 is pyrrolidino, piperidino, perhydroazepino or morpholino, RX is an inorganic acid, organic acid or an alkyl bromide or iodide, m is 3 or 4, and n is zero or one. The compounds are prepared by (1) reacting benzothienyl-lithium with STR3 followed by hydrolysis, or (2) when the substituent is located at the 2 position of the benzothienyl group, by reacting benzothiophene with STR4 followed by reaction with STR5 The compounds possess blood-plaque aggregation, spasmolytic, analgesic, anti-inflammatory and coronary, cerebral and peripheral vaso-dilatory properties.