61508-55-2Relevant academic research and scientific papers
Domiodol: Separation of cis and trans isomers and comparison of their pharmacological activity
Riva,Gentili,Kogi,Saito,Cantarelli,Ravenna
, p. 1091 - 1093 (2007/10/02)
Cis and trans isomers of 2-iodomethyl-4-hydroxymethyl-1,3-dioxolane (domiodol, MG 13 608) were separated by preparative GLC and prepared on a larger scale by previous resolution of an intermediate. Acute toxicity and effect on respiratory tract excretion were evaluated for domiodol and for each isomer: no significant differences were found.
