615252-70-5Relevant articles and documents
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides
Mai, Antonello,Massa, Silvio,Pezzi, Riccardo,Simeoni, Silvia,Rotili, Dante,Nebbioso, Angela,Scognamiglio, Annamaria,Altucci, Lucia,Loidl, Peter,Brosch, Gerald
, p. 3344 - 3353 (2007/10/03)
Chemical manipulations performed on aroyl-pyrrolyl-hydroxyamides (APHAs) led to (aryloxopropenyl)pyrrolyl hydroxamates 2a-w, and their inhibition against maize HDACs and their class I or class II HDAC selectivity were determined. In particular, from these