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6154-04-7

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6154-04-7 Usage

Description

5-Amino-2-methyl-2H-tetrazole is a chemical compound characterized by the molecular formula C2H6N6. It presents as a white crystalline solid that is soluble in water and exhibits a melting point of 176-177 degrees Celsius. 5-Amino-2-methyl-2H-tetrazole is recognized for its utility in various industrial applications, including the synthesis of pharmaceuticals, agrochemicals, dyes, and pigments, as well as its role in stabilizing rocket propellants and explosives. Despite its stability under normal conditions, it is advised to handle 5-Amino-2-methyl-2H-tetrazole with caution due to its potential hazardous properties.

Uses

Used in Pharmaceutical and Agrochemical Industries:
5-Amino-2-methyl-2H-tetrazole is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to contribute to the development of new and effective compounds.
Used in Dye and Pigment Production:
In the dye and pigment industry, 5-Amino-2-methyl-2H-tetrazole is employed as a key component in the production of dyes and pigments, leveraging its chemical properties to enhance color characteristics and stability.
Used in Rocket Propellant and Explosive Stabilization:
5-Amino-2-methyl-2H-tetrazole is used as a stabilizer for rocket propellants and explosives, ensuring the safety and reliability of these materials during storage and use.

Check Digit Verification of cas no

The CAS Registry Mumber 6154-04-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,5 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6154-04:
(6*6)+(5*1)+(4*5)+(3*4)+(2*0)+(1*4)=77
77 % 10 = 7
So 6154-04-7 is a valid CAS Registry Number.
InChI:InChI=1/C2H5N5/c1-7-5-2(3)4-6-7/h1H3,(H2,3,5)

6154-04-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Amino-2-Methyl-2H-Tetrazole

1.2 Other means of identification

Product number -
Other names 2-methyltetrazol-5-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6154-04-7 SDS

6154-04-7Relevant articles and documents

Synthesis and antileishmanial activity of 1,2,4,5-tetraoxanes against leishmania donovani

Cabral, Lília I.L.,Pomel, Sébastien,Cojean, Sandrine,Amado, Patrícia S.M.,Loiseau, Philippe M.,Cristiano, Maria L.S.

supporting information, (2020/02/11)

A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 μm. The most active tetraoxane, compound LC140, exhibited an IC50 value of 2.52 ± 0.65 μm on L. donovani intramacrophage amastigotes, with a selectivity index of 13.5. This compound reduced the liver parasite burden of L. donovani-infected mice by 37% after an intraperitoneal treatment at 10 mg/kg/day for five consecutive days, whereas miltefosine, an antileishmanial drug in use, reduced it by 66%. These results provide a relevant basis for the development of further tetraoxanes as effective, safe, and cheap drugs against leishmaniasis.

NEW ENDOPEROXIDE COMPOUNDS, PROCESS FOR OBTAINING THEM AND USES THEREOF FOR CONTROL OF PERKINSIOSIS IN BIVALVES

-

Page/Page column 22-23, (2020/12/11)

The present invention relates to new endoperoxide compounds and compositions, and to a process for producing them for prophylaxis and control of perkinsiosis in bivalves. Endoperoxide compounds with biological activity against Perkinsus olseni include 13

In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of saccharin–tetrazolyl and –thiadiazolyl derivatives: The simple dependence of the ph value on antimicrobial activity

Frija, Luís M. T.,Ntungwe, Epole,Sitarek, Przemys?aw,Andrade, Joana M.,Toma, Monika,?liwiński, Tomasz,Cabral, Lília,Cristiano, M. Lurdes S.,Rijo, Patrícia,Pombeiro, Armando J. L.

, (2019/11/20)

The antimicrobial, antioxidant, and cytotoxic activities of a series of saccharin–tetrazolyl and –thiadiazolyl analogs were examined. The assessment of the antimicrobial properties of the referred-to molecules was completed through an evaluation of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values against Gram-positive and Gram-negative bacteria and yeasts. Scrutiny of the MIC and MBC values of the compounds at pH 4.0, 7.0, and 9.0 against four Gram-positive strains revealed high values for both the MIC and MBC at pH 4.0 (ranging from 0.98 to 125 μg/mL) and moderate values at pH 7.0 and 9.0, exposing strong antimicrobial activities in an acidic medium. An antioxidant activity analysis of the molecules was performed by using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, which showed high activity for the TSMT (N-(1-methyl-2H-tetrazol-5-yl)-N-(1,1-dioxo-1,2-benzisothiazol-3-yl) amine, 7) derivative (90.29% compared to a butylated hydroxytoluene positive control of 61.96%). Besides, the general toxicity of the saccharin analogs was evaluated in an Artemia salina model, which displayed insignificant toxicity values. In turn, upon an assessment of cell viability, all of the compounds were found to be nontoxic in range concentrations of 0–100 μg/mL in H7PX glioma cells. The tested molecules have inspiring antimicrobial and antioxidant properties that represent potential core structures in the design of new drugs for the treatment of infectious diseases.

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