6154-31-0Relevant academic research and scientific papers
Synthesis of nucleoside mono-, di-, and triphosphoramidates from solid-phase cyc/osaligenyl phosphitylating reagents
Ahmadibeni, Yousef,Tiwari, Rakesh K.,Sun, Gongqin,Parang, Keykavous
supporting information; experimental part, p. 2157 - 2160 (2009/09/28)
Chloromethyl polystyrene resin was reacted with 5-hydroxysalicylaldehyde in the presence of potassium carbonate to afford polymer-bound 2-hydroxybenzaldehyde. Subsequent reduction with borane solution produced polymer-bound 2-hydroxybenzyl alcohol. The re
ADENOSINE CYCLIC 3',5'-PHOSPHORAMIDATE AND N,N-DIMETHYLPHOSPHORAMIDATE: SYNTHESIS VIA SYMMETRICAL AND MIXED ANHYDRIDES AND HYDROLYSIS
Tomasz, Jenoe,Bottka, Sandor,Ludwig, Janos,Pelczer, Istvan
, p. 597 - 600 (2007/10/02)
The title compounds were synthesized by converting cyclic AMP with a sulfonyl chloride to the symmetrical anhydride or with diphenyl phosphorochloridate to the mixed anhydride, then aminolyzing the anhydrides without isolation.The synthesis preferentially gave SP-amides.Characteristic differences were observed in the behavior of the unsubstituted amide and the dimethylamide under hydrolysis conditions.
