6154-39-8 Usage
General Description
Z-GLY-GLN-OH, also known as Z-glycylglutamine, is a dipeptide molecule composed of the amino acids glycine and glutamine attached to a Z-protection group. This chemical compound is commonly used in peptide synthesis as a building block for creating longer peptides and proteins. The Z-protection group is added to the amino terminus of the glycine residue to prevent unwanted reactions during peptide synthesis. Z-GLY-GLN-OH has applications in pharmaceutical research and drug development, as well as in biochemical studies and peptide chemistry. Additionally, it is used as a model compound in studies related to the synthesis and properties of peptides.
Check Digit Verification of cas no
The CAS Registry Mumber 6154-39-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,5 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6154-39:
(6*6)+(5*1)+(4*5)+(3*4)+(2*3)+(1*9)=88
88 % 10 = 8
So 6154-39-8 is a valid CAS Registry Number.
6154-39-8Relevant articles and documents
Peptide coupling of unprotected amino acids through in situ p-nitrophenyl ester formation
Gagnon, Paul,Huang, Xicai,Therrien, Eric,Keillor, Jeffrey W.
, p. 7717 - 7719 (2007/10/03)
Several series of dipeptides and tripeptides were prepared via an activation-coupling method involving the in situ formation of a p-nitrophenyl ester of an (N-protected) amino acid, followed by coupling with an unprotected amino acid in partially aqueous solutions. The resulting peptide is easily isolated by precipitation. In general, the yields obtained are good to excellent and racemization is minimal. This method is particularly advantageous with respect to its simplicity and lack of obligatory side chain protection/deprotection steps.
