61544-61-4Relevant academic research and scientific papers
Benzylpyrimidines
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, (2008/06/13)
Benzylpyrimidines of the formula STR1 wherein R1 and R2 each, independently, is amino, optionally C1-3 -alkyl-substituted pyrrolo, pyrrolidino, piperidino, -NHR3, -N(R3)2, -NHR4, -N(R3)(R4),-NR3 COOR3, -NHCOOR3, -NHCONHR3, -NHCONH2 or -N(NO)R3 or wherein R3 is C1-4 -alkyl or C2-4 -alkenyl, R4 is acyl; Z is hydrogen, chlorine, bromine, pyrrolo, pyrrolidino, piperidino or morpholino or R3, OR3 or -N(R3)2 ; A is an oxygen atom bonded to one of the cyclic nitrogen atoms; and n is 0 or 1 are prepared. The benzylpyrimidines are useful as potentiators of the activity of the sulfonamides.
