61551-69-7

Basic information

• Product Name: 2,2'-AZOBIS[2-METHYL-N-(2-HYDROXYETHYL)PROPIONAMIDE]
• Synonyms: -(1,2-DIAZENEDIYL)BIS[N-(2-HYDROXYETHYL)-2-METHYLPROPANAMIDE;2,2'-AZOBIS[2-METHYL-N-(2-HYDROXYETHYL)PROPIONAMIDE];2,2''-Azobis-[N-(2-hydroxyethyl)-2-methyl)-propionamide;2,2'-azobis[N-(2-hydroxyethyl)]-2-methylpropanamide;2,2'-Azobis[2-methyl-N-(2-hydroxyethyl)propanamide];2,2'-Azobis[N-(2-hydroxyethyl)isobutyramide];N,N'-Bis(2-hydroxyethyl)[2,2'-azobis(2-methylpropanamide)];VA-086
• CAS NO: 61551-69-7
• Molecular Formula: C12H24N4O4
• Molecular Weight: 288.34
• EINECS: 1312995-182-4
• Mol File: 61551-69-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 537.1 °C at 760 mmHg
• Flash Point: 278.7 °C
• Appearance: /
• Density: 1.19
• PKA: 13.95±0.46(Predicted)
• CAS DataBase Reference: 2,2'-AZOBIS[2-METHYL-N-(2-HYDROXYETHYL)PROPIONAMIDE](CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-AZOBIS[2-METHYL-N-(2-HYDROXYETHYL)PROPIONAMIDE](61551-69-7)
• EPA Substance Registry System: 2,2'-AZOBIS[2-METHYL-N-(2-HYDROXYETHYL)PROPIONAMIDE](61551-69-7)

Safety Data

• Hazardous Substances Data: 61551-69-7(Hazardous Substances Data)

Usage

General Description

2,2'-Azobis[2-methyl-N-(2-hydroxyethyl)propionamide], often shortened to 2,2'-Azobis, is an organic compound. It is a derivative of azobisisobutyronitrile (AIBN), a popular radical initiator in polymer chemistry. As a white powder, it's used as a radical polymerization initiator in the production of various polymers and plastics. Its benefits include a convenient decomposition rate, a high yield of free radicals, and a relatively low purification requirement. It contributes to the formation of crosslinking structures and certain complex molecular architectures. Due to it being associated with the thermal generation of radicals, it is necessary to handle it with proper safety measures in order to prevent hazardous situations.

Upstream product

• 2589-57-3 dimethyl 2,2'-azobis(isobutyrate) 
• 141-43-5 ethanolamine 

Downstream Products

• 204978-87-0 2',5'-di-O-acetyl-3'-deoxy-inosine 

Relevant articles and documents

2,2'-azo(2-methyl-N-(2-hydroxyethyl)propionamide) preparation method

The invention discloses a 2,2'-azo(2-methyl-N-(2-hydroxyethyl)propionamide) preparation method, which comprises: adding 2,2'-azobisisobutyronitrile, methanol and toluene to a reactor having a stirring and reflux device, starting stirring, slowly introducing hydrogen chloride gas under cooling, and controlling the temperature of the material and carrying out a thermal insulation reaction; after completing the reaction, adding the reaction liquid into water in a dropwise manner, carrying out a hydrolysis reaction, layering after completing the hydrolysis, adding a small amount of methanol to the organic phase, and carrying out pressure reducing distillation for a certain time; after completing the distillation, slowly adding the organic phase into a mixed solution of sodium methoxide and monoethanolamine in a dropwise manner, and carrying out thermal insulation; after completing the thermal insulation, carrying out solid-liquid separation by a centrifuge, continuously washing the solid with water, crystallizing, carrying out centrifugation until the material is dried, placing the material in a drying device, and drying; and after the drying, cooling the material to a normal temperature to obtain the 2,2'-azo(2-methyl-N-(2-hydroxyethyl)propionamide) product, wherein the product content (HPLC) is more than 98%, and the yield is 55-75%.