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61552-41-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 61552-41-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,5,5 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 61552-41:
108 % 10 = 8
So 61552-41-8 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name 5-[2-amino-6-(3-methyl-5-nitroimidazol-4-yl)sulfanylpurin-9-yl]-2-(hydroxymethyl)oxolan-3-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61552-41-8 SDS

61552-41-8Downstream Products

61552-41-8Relevant articles and documents

Nucleosides of Azathioprine and Thiamiprine as Antiarthritics

Krenitsky, Thomas A.,Hall, Willard W.,Selph, Jeffrey L.,Truax, James F.,Vinegar, Ralph

, p. 1471 - 1475 (1989)

Azathioprine -1H-purine> is a widely used immunosuppressive and antiarthritic drug.For the sake of comparison, the riboside, the 2'-deoxyriboside, and the arabinoside of azathioprine and its 2-amino congener, thiamiprine, were prepared by an enzymatic method.In vitro, the cytotoxicities of these aglycones and their nucleosides were similar (ED 50 = 0.8-2 μM), except for the arabinoside, which were nontoxic (ED 50 > 100 μM).In vivo, their activities were compared in the rat adjuvant arthritis model.The ribosides and 2'-deoxyribosides were less potent than their corresponding aglycons.The safety indexes of these nucleosides were comparable to those of the corresponding aglycons except for the 2'-deoxyriboside of azathioprine, which had an appreciable lower safety index than did azathioprine.Both arabinosides were inactive and nontoxic.All of the aglycons tested (6-mercaptopurine, azathioprine, 6-thioguanine, and thiamiprine) were of similar potency.However, azathioprine had a more favorable therapeutic index than did 6-mercaptopurine.Similarly, thiamiprine was safer than was 6-thiaguanine.In this model, the S-(1-methyl-4-nitro-1H-imidazol-5-yl) moiety impared greater safety to these thiopurines by decreasing toxicity but not affecting potency.

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