61554-69-6

Basic information

• Product Name: 3-(2-Methylphenyl)-2-[(propylthio)methyl]quinazolin-4(3H)-one
• Synonyms: 3-(2-Methylphenyl)-2-[(propylthio)methyl]quinazolin-4(3H)-one
• CAS NO: 61554-69-6
• Molecular Formula: C19H20N2OS
• Molecular Weight: 324.4399
• Mol File: 61554-69-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 477.2°Cat760mmHg
• Flash Point: 242.4°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 2.86E-09mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: 3-(2-Methylphenyl)-2-[(propylthio)methyl]quinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Methylphenyl)-2-[(propylthio)methyl]quinazolin-4(3H)-one(61554-69-6)
• EPA Substance Registry System: 3-(2-Methylphenyl)-2-[(propylthio)methyl]quinazolin-4(3H)-one(61554-69-6)

Safety Data

• Hazardous Substances Data: 61554-69-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H20N2OS/c1-3-12-23-13-18-20-16-10-6-5-9-15(16)19(22)21(18)17-11-7-4-8-14(17)2/h4-11H,3,12-13H2,1-2H3

Relevant articles and documents

Synthesis and central nervous system activity of quinazolones related to 2 methyl 3 (o tolyl) 4 (3H) quinazolone (methaqualone)

A number of derivatives of 2-methyl-3-(o-tolyl)-4(3H)-quinazolone bearing new substituents on the 2-methyl group have been synthesized. It was established that most substitutions at this position reduce or remove the CNS depressant activity of methaqualone. From the series prepared only the 2-fluoromethyl derivative or certain isothiouronium salts, which could be hydrolyzed in vivo to the 2-mercaptomethyl derivative, showed activity of the same magnitude as methaqualone.