615563-76-3Relevant academic research and scientific papers
Tridentate nitrogen phosphine ligand containing arylamine NH as well as preparation method and application thereof
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Paragraph 0095-0102; 0105-0109, (2021/06/26)
The invention discloses a tridentate nitrogen phosphine ligand containing arylamine NH as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis. The tridentate nitrogen phosphine ligand disclosed by the invention is the first case of tridentate nitrogen phosphine ligand containing not only a quinoline amine structure but also chiral ferrocene at present, a noble metal complex of the type of ligand shows good selectivity and extremely high catalytic activity in an asymmetric hydrogenation reaction, meanwhile, a cheap metal complex of the ligand can also show good selectivity and catalytic activity in the asymmetric hydrogenation reaction, and is very easy to modify in the aspects of electronic effect and space structure, so that the ligand has huge potential application value. A catalyst formed by the ligand and a transition metal complex can be used for catalyzing various reactions, can be used for synthesizing various drugs, and has important industrial application value.
A Green approach towards the synthesis of chiral alcohols using functionalized alginate immobilized Saccharomyces cerevisiae cells
Muthineni, Narmada,Arnipally, Manikanta Swamy,Bojja, Sridhar,Meshram, Harshadas Mitaram,Srivastava, Ajay Kumar,Adari, Bhaskar Rao
, p. 233 - 237 (2016/12/09)
The stereochemistry of the drug molecule is gaining greater therapeutic importance and thus much attention was drawn in synthesis of chiral compounds by the pharmaceutical industry. In this study Saccharomyces cerevisiae cells immobilized on functionalize
The stereodivergent asymmetric synthesis of a range of 2-(1′- hydroxyalkyl)phenols
Davies, Stephen G.,Hume, W. Ewan,Roberts, Paul M.,Thomson, James E.
experimental part, p. 8076 - 8088 (2010/10/19)
The use of the (S)-α-methylbenzyl group as a chiral auxiliary has allowed the diastereoselective ortho-deprotonation of a chromium tricarbonyl complexed phenoxy ring. When the resultant ortho-anion is treated with an aldehyde two diastereoisomeric complex
Chiral amide from (1S,2R)-(+)-norephedrine alkaloid in the enantioselective addition of diethylzinc to aryl and heteroaryl aldehydes
Ananthi, Nallamuthu,Balakrishnan, Umesh,Vinu, Ajayan,Ariga, Katsuhiko,Velmathi, Sivan
experimental part, p. 1731 - 1735 (2009/12/24)
Chiral amide synthesized from (1S,2R)-(+)-norephedrine and furoic acid was found to catalyze the enantioselective ethylation of aromatic and heteroaromatic aldehydes to secondary alcohols with 99.8% enantioselectivity at 0 °C without the addition of a promoter such as titanium tetraisopropoxide.
