615576-59-5Relevant academic research and scientific papers
SULFONAMIDE DERIVATIVES
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Page/Page column 36-37, (2010/02/07)
Sulfonamide derivatives of formula (1) are described wherein X is an O or S atom; Y is an 0 or S atom; A is a group -S02NR1R2; m is zero or the integer 1; n is zero or the integer 1; provided that at least one but not both of m and n are the integer 1; R3 is a hydrogen atom or an alkyl or cycloalkyl group; and the salts, solvates, hydrates, tautomers, isomers, N-oxides thereof. The compounds are potent inhibitors of IMPDH and are of use as immunosuppressants, anti-cancer agents, anti-inflammatory agents, antipsoriatic and anti-viral agents.
