Welcome to LookChem.com Sign In|Join Free
  • or
(3R)-1-[(20S)-20-(Dimethylamino)-4-oxo-5α-pregnan-3β-yl]-3-isopropylazetidin-2-one is an alkaloid derived from Pachysandra terminalis Sieb. et Zucco, a plant species. (3R)-1-[(20S)-20-(Dimethylamino)-4-oxo-5α-pregnan-3β-yl]-3-isopropylazetidin-2-one features the pregnane skeleton, which is common among alkaloids found in this plant. It is dextrorotatory with a specific rotation of [α]D + 24° (CHCI3). The molecule contains two keto groups, one of which is part of a four-membered ring. Upon reduction with sodium borohydride (NaBH4), it yields Pachystermine B. The structure of this alkaloid has been confirmed through partial synthesis.

6156-99-6

Post Buying Request

6156-99-6 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

6156-99-6 Usage

Uses

1. Used in Pharmaceutical Industry:
(3R)-1-[(20S)-20-(Dimethylamino)-4-oxo-5α-pregnan-3β-yl]-3-isopropylazetidin-2-one is used as a pharmaceutical compound for its potential therapeutic applications. The presence of the pregnane skeleton and its unique structural features make it a promising candidate for the development of new drugs targeting various health conditions.
2. Used in Chemical Research:
This alkaloid is also utilized in chemical research for understanding the structure-activity relationships of pregnane-based compounds. Its synthesis and reduction to Pachystermine B provide valuable insights into the chemical properties and potential modifications that can be made to enhance its pharmacological effects.
3. Used in Natural Product Chemistry:
(3R)-1-[(20S)-20-(Dimethylamino)-4-oxo-5α-pregnan-3β-yl]-3-isopropylazetidin-2-one serves as an example of the diverse range of alkaloids found in nature, particularly within the Pachysandra terminalis plant. Its study contributes to the broader understanding of natural product chemistry and the potential for discovering new bioactive compounds with medicinal properties.

References

Kikuchi, Uyeo., Tetrahedron Lett., 3473 (1965) Kikuchi, Uyeo., Chem. Pharm. Bull., 15, 549 (1967) Partial synthesis: Kikuchi et al., Tetrahedron Lett., 909 (1968)

Check Digit Verification of cas no

The CAS Registry Mumber 6156-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,5 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6156-99:
(6*6)+(5*1)+(4*5)+(3*6)+(2*9)+(1*9)=106
106 % 10 = 6
So 6156-99-6 is a valid CAS Registry Number.
InChI:InChI=1/C29H48N2O2/c1-17(2)20-16-31(27(20)33)25-13-15-29(5)23-12-14-28(4)21(18(3)30(6)7)10-11-22(28)19(23)8-9-24(29)26(25)32/h17-25H,8-16H2,1-7H3/t18?,19-,20-,21-,22-,23-,24-,25-,28+,29+/m0/s1

6156-99-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name pachystermine A

1.2 Other means of identification

Product number -
Other names Pachystermin A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6156-99-6 SDS

6156-99-6Upstream product

6156-99-6Downstream Products

6156-99-6Relevant academic research and scientific papers

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 6156-99-6