61562-68-3Relevant academic research and scientific papers
Novel 1,3-benzodioxaneprostanoic acid derivatives and process for the preparation thereof
-
, (2008/06/13)
1,3-Benzodioxaneprostanoic acid compound of the formula STR1 wherein R1 is hydroxy, alkoxy of 1-10 carbon atoms, methylsulfamido, substituted or unsubstituted aryloxy, or O--CH2 --U--V wherein U is a direct bond, carbonyl, or carbonyloxy, and V is phenyl or phenyl substituted, e.g. by one or more of phenyl, phenoxy, alkoxy of 1-2 carbon atoms, and halogen; A is --CH2 --CH2 -- or trans --CH=CH--; B is --CH2 --CH2 -- or cis- or trans--CH=CH--; Z is hydroxymethylene or carbonyl; X Y, if Z is hydroxymethylene, is STR2 or, if Z is carbonyl, is STR3 or --CH=CH--; R2 is hydrogen or alkyl of 1-5 carbon atoms; R3 and R4 each are H, F, Cl, Br, I or CF3, CH3 or alkoxy of 1-2 carbon atoms or R3 and R4 in 6-,7-position is methylendioxy; and if R1 is hydroxy, salts thereof with pharmaceutically acceptable bases, are agents for inducing menstruation, interrupting pregnancy, inducing labor and synchronizing the sexual cycle in female mammals.
