61567-62-2

Basic information

• Product Name: cis-dichlorobis(chlorodiphenylphosphine)palladium(II)
• CAS NO: 61567-62-2
• Molecular Weight: 618.602
• Mol File: 61567-62-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: cis-dichlorobis(chlorodiphenylphosphine)palladium(II)(CAS DataBase Reference)
• NIST Chemistry Reference: cis-dichlorobis(chlorodiphenylphosphine)palladium(II)(61567-62-2)
• EPA Substance Registry System: cis-dichlorobis(chlorodiphenylphosphine)palladium(II)(61567-62-2)

Safety Data

• Hazardous Substances Data: 61567-62-2(Hazardous Substances Data)

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 15617-18-2 bis(benzonitrile)palladium(II) dichloride 

Downstream Products

• 1021176-45-3 chloro-(pyrine-6-thiolato)(chloro-diphenylphosphine)palladium(II) 
• 1218949-04-2 [Pd(1,2,3,4-tetrahydroisoquinolinedithiocarbamate)(diphenylchlorophosphine)Cl] 
• 1218949-06-4 [Pd(4-methylpiperidinedithiocarbamate)(diphenylchlorophosphine)Cl] 
• 1218949-09-7 [Pd(N-methylpiperazinedithiocarbamate)(diphenylchlorophosphine)Cl] 

Relevant articles and documents

Phosphinito palladium(ii) complexes as catalysts for the synthesis of 1,3-enynes, aromatic alkynes and ynones

An air-stable phosphinito palladium(ii) complex (Ph1-Phoxide) has been found to be an efficient catalyst in the formation of C-C bonds. The coupling of terminal alkynes formed gem-1,3-enynes as the only reaction products. Aromatic alkynes can be synthesized from the coupling of terminal alkynes and haloaromatic compounds (Sonogashira coupling). The phosphinito palladium(ii) complex also catalyses the coupling between acyl chlorides and terminal alkynes (Sonogashira coupling), furnishing ynones in excellent yields.

Synthesis, characterization, in vitro cytotoxicity and anti-inflammatory activity of palladium(II) complexes with tertiary phosphines and heterocyclic thiolates: Crystal structure of [PdC28H19N8PS2]

The new four-coordinated mononuclear palladium(II) complexes 1-9 with chelating heterocyclic thiolates and tertiary phosphines with general formula [Pd(L)nCl(R′R2P)] (L = Pym2SH (pyrimidine-2-thiolate), Pur6SH (purine-6-thiolate), Py2SH (pyridine-2-thiolate), R3P = PPh3, P(o-tolyl)3, PPh2Cl), n = 1, 2) have been synthesized by the direct reaction of [PdCl2(R′R2P)2] with polyfunctional heterocyclic thiolates which display a wide variety of coordinations. These compounds were characterized by elemental analysis, FT-IR and multinuclear (1H, 13C and 31P) NMR. The X-ray diffraction study of non-ionic compound 5 showed that the thiolate acts as unidentate and that the chelating (-N,S) ligand adopts a slightly distorted square planar geometry around the palladium atom. In vitro the anti-inflammatory inhibition of compounds 1-9 was 10-15% greater than that of the standard drug Declofenac. Compounds 1 and 4 showed mostly a moderate to low cytotoxicity against seven human tumor cell lines whereas compound 3 was somewhat more active.