61580-72-1

Upstream product

• 17874-17-8 cyclohex-1-enyl-trimethyl-silane 
• 92120-18-8 2-chloro-2-trimethylsilylcyclohexanone 
• 92120-14-4 t-2-chloro-2-trimethylsilylcyclohexan-r-1-ol 
• 92120-15-5 1-trimethylsilyl-t-2-chlorocyclohexan-r-1-ol 

Downstream Products

• 92131-65-2 4-Nitro-benzoic acid (1R,2R)-2-bromo-2-trimethylsilanyl-cyclohexyl ester 
• 92120-17-7 2-bromo-2-trimethylsilylcyclohexanone 
• 61580-71-0 1-trimethylsilyl-trans-cyclohexane-1,2-diol 
• 61580-73-2 t-2-methoxy-2-trimethylsilylcyclohexan-r-1-ol 
• 92120-13-3 t-2-ethoxy-2-trimethylsilylcyclohexan-r-1-ol 

Relevant academic research and scientific papers

Comparison Between the Epoxide Ring-opening of 1-Trimethylsilylcyclohexene Oxide and Some Electrophilic Additions to 1-Trimethylsilylcyclohexene

The reactions of 1,2-epoxy-1-trimethylsilylcyclohexane (1) with several nucleophilic reagents under acidic conditions have been studied and the ring-opened products identified.In all cases ring-opening occurs in a trans fashion with attack by the nucleoph

Some Epoxide Ring-opening Reactions of αβ-Epoxysilanes

Epoxide ring-opening of 1,2-epoxy-1-trimethylsilylcyclohexane (3) has given a range of the 2-substituted 2-trimethylsilylcyclohexanols (4; X = H, OH, OMe, OCH2CH=CH2, Br, I, SCN) in which attack by nucleophile has occured at the carbon α to silicon.The products (4) have been transformed into a number of functionalised silanes, including the silyl-episulphide (9).Other epoxides which have been less extensively studied are the conformationally biased epoxysilanes (10) and (11), the eight-membered ring epoxysilanes (17) and (21) and the two stereoisomeric 2,3-epoxy-3-trimethylsilylpentanes (26) and (29).Epoxide ring-opening adducts were obtained after treatment with H+-MeOH in all cases except for compound (17), where the bicyclic alcohol (18) was formed by a transannular reaction.