61593-75-7

Usage

Type of Drug

Platinum-based chemotherapy drug

Purpose

Treats certain types of cancer, including testicular and ovarian cancer

Mechanism of Action

Interferes with the DNA replication process of cancer cells, leading to their destruction

Administration

Intravenous

Combination Therapy

Often used in combination with other chemotherapy drugs to maximize effectiveness

Side Effects

Nausea, vomiting, bone marrow suppression

Potential Risks

Kidney damage and nerve damage, particularly at high doses

Monitoring

Use is closely monitored by healthcare professionals

InChI:InChI=1/C6H14N2O4S.Pt/c7-5-3-1-2-4-6(5,8)12-13(9,10)11;/h5H,1-4,7-8H2,(H,9,10,11);/q;+2/p-1

Upstream product

• 38780-40-4 {(1R,2R)-cyclohexane-1,2-diamine}dichloridoplatinum(II) 
• 66845-32-7 trans-cyclohexamethylene diaminediiodoplatinum(II) 
• 61848-66-6 cis-dichloro-(cis-1,2-diaminocyclohexane)platinum(II) 

Downstream Products

• 96322-20-2 ((CH₂)4CHCCOO)2Pt(NH₂(C₆H₁₀)NH₂) 
• 96322-13-3 bis(cyclohexanecarboxylato)(1,2-diaminocyclohexane)platinum(II) 
• 99144-84-0 ((C₆H₁₁)CH₂COO)2Pt(NH₂(C₆H₁₀)NH₂) 

Relevant academic research and scientific papers

Metal-polysaccharide conjugates: compositions, synthesis and methods for cancer therapy

The current disclosure, in one embodiment, includes a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid having an O-group covalently bound to the polysaccharide. The conjugate also has at least one metal conjugated by the O-group of the amino acid. According to another embodiment, the disclosure provides a method of synthesizing a polysaccharide conjugate by covalently bonding a monomeric amino acid having an O-group to a polysaccharide and by conjugating a metal to the O-group to form a polysaccharide conjugate. According to a third embodiment, the disclosure relates to a method of killing a cancer cell by administering to the cell an effective amount of a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid having an O-group covalently bound to the polysaccharide. The conjugate also has at least one metal conjugated by the O-group of the amino acid.