616242-06-9Relevant academic research and scientific papers
A ligand-based virtual screening approach to identify small molecules as hERG channel activators
Giacomini, Elisa,Buonfiglio, Rosa,Masetti, Matteo,Wang, Yuhong,Tseng, Gea-Ny,Roberti, Marinella,Recanatini, Maurizio
, p. 269 - 280 (2015)
The hERG potassium channel is currently emerging as a potential target for the treatment of some forms of arrhythmias or to contrast an unintentional channel block caused by drugs. Despite its therapeutic relevance, so far only few compounds are described
