61628-05-5 Usage
Uses
Used in Organic Synthesis:
(3aR,4R,5R,6aS)-hexahydro-5-tert-butyldimethylsilyloxy-4-[(1E,3S)-3-tert-butyldimethylsilyloxy-(1E)-octenyl]-2H-cyclopenta[β]furan-2-one is used as a key intermediate in organic synthesis for the development of novel compounds with potential applications in various fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (3aR,4R,5R,6aS)-hexahydro-5-tert-butyldimethylsilyloxy-4-[(1E,3S)-3-tert-butyldimethylsilyloxy-(1E)-octenyl]-2H-cyclopenta[β]furan-2-one is utilized as a building block for the design and synthesis of new pharmaceutical agents. Its unique structure may contribute to the discovery of innovative drugs with improved therapeutic properties.
Used in Chemical Engineering:
(3aR,4R,5R,6aS)-hexahydro-5-tert-butyldimethylsilyloxy-4-[(1E,3S)-3-tert-butyldimethylsilyloxy-(1E)-octenyl]-2H-cyclopenta[β]furan-2-one is employed in chemical engineering for the development of new materials and processes. Its versatile structure allows for the creation of advanced materials with specific properties tailored for various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 61628-05-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,6,2 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61628-05:
(7*6)+(6*1)+(5*6)+(4*2)+(3*8)+(2*0)+(1*5)=115
115 % 10 = 5
So 61628-05-5 is a valid CAS Registry Number.
61628-05-5Relevant academic research and scientific papers
Zhu, Kejie,Hu, Sha,Liu, Minjie,Peng, Haihui,Chen, Fen-Er
, p. 9923 - 9927 (2019)
A new protocol for the construction of a crucial bicyclic lactone of prostaglandins using a stereocontrolled organocatalytic Baeyer–Villiger (B-V) oxidation was developed. The key B-V oxidation of a racemic cyclobutanone derivative with aqueous hydrogen peroxide has enabled an early-stage construction of a bicyclic lactone skeleton in high enantiomeric excess (up to 95 %). The generated bicyclic lactone is fully primed with two desired stereocenters and enabled the synthesis of the entire family of prostaglandins according to Corey′s route. Furthermore, the reactivity and enantioselectivity of B-V oxidation of racemic bicyclic cyclobutanones were evaluated and 90–99 % ee was obtained, representing one of the most efficient routes to chiral lactones. This study further facilitates the synthesis of prostaglandins and chiral lactone-containing natural products to promote drug discovery.
