61640-40-2Relevant academic research and scientific papers
Thioimidazolium Ionic Liquids as Tunable Alkylating Agents
Guterman, Ryan,Miao, Han,Antonietti, Markus
, p. 684 - 689 (2018)
Alkylating ionic liquids based on the thioimidazolium structure combine the conventional properties of ionic liquids, including low melting point and nonvolatility, with the alkylating function. Alkyl transfer occurs exclusively from the S-alkyl position, thus allowing for easy derivatization of the structure without compromising specificity. We apply this feature to tune the electrophilicty of the cation to profoundly affect the reactivity of these alkylating ionic liquids, with a caffeine-derived compound possessing the highest reactivity. Anion choice was found to affect reaction rates, with iodide anions assisting in the alkylation reaction through a shuttling process. The ability to tune the properties of the alkylating agent using the toolbox of ionic liquid chemistry highlights the modular nature of these compounds as a platform for alkylating agent design and integration in to future systems.
METHOD FOR ALKYLATING A MOLECULE OR AN ION
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Page/Page column 37, (2019/04/16)
The present invention relates to a method for alkylating a molecule or an ion, wherein the molecule or the ion is alkylated by reacting it with an alkylating agent, wherein the alkylating agent is a compound according to formula (1) or a compound according to formula (4). In the formulae (1) and (4), R1 is a substituted C1-20-alkyl group, an unsubstituted C1-20-alkyl group, a substituted C3-20-cycloalkyl group or an unsubstituted C3-20-cycloaalkyl group, R2 is a substituted or unsubstituted C1-20 hydrocarbon residue or a hydrogen atom, R3 is a substituted or unsubstituted C1-20 hydrocarbon residue or a hydrogen atom, R4 and R5 are linked with each other to form an aromatic group or are independently from each other selected from the group consisting of a hydrogen atom, substituted and unsubstituted C1-20 hydrocarbon residues and electron withdrawing groups, R10 to R13 are independently from each other selected from the group consisting of a hydrogen atom, a substituted C1-20-alkyl group, an unsubstituted C1-20-alkyl group, a substituted C3-20-cycloalkyl group and an unsubstituted C3-20-cycloaalkyl group and A- is an anion.
