61642-89-5

Usage

Uses

Used in Antimicrobial Applications:
Atractylodinol is used as an antimicrobial agent for its differential antimicrobial activity, which can be effective against various pathogens.
Used in Veterinary Medicine:
In the veterinary industry, Atractylodinol is used as an antiviral agent for the inhibition of PRRSV, a virus that causes significant economic losses in the pig farming industry. Its use can help in controlling the spread of the virus and improving the health of the animals.
Used in Drug Development:
Atractylodinol's potent inhibitory effects on PRRSV make it a promising candidate for the development of new antiviral drugs, particularly for the treatment of porcine reproductive and respiratory syndrome.

InChI:InChI=1/C13H10O2/c14-11-7-5-3-1-2-4-6-9-13-10-8-12-15-13/h5-10,12,14H,11H2/b7-5+,9-6+

Upstream product

• 860638-18-2 (Z)-2-(4-trimethylsilylbut-1-en-3-ynyl)furan 
• 6071-41-6 (E)-5-bromo-2-penten-4-yn-1-ol 
• 35042-52-5 (E)-2-penten-4-yn-1-ol 
• 55290-63-6 2-[(1E,7E)-nona-1,7-diene-3,5-diyn-1-yl]furan 
• 623-30-3 3-furan-2-yl-propenal 
• 3752-22-5 (E)-2-(but-1-en-3-yn-1-yl)furan 

Relevant academic research and scientific papers

A direct synthesis of atractylodinol, a potent inhibitor of PRRSV, and its biological evaluation

A direct synthesis of atractylodinol from 2-furylbutenyne and bromoacetylene 6 is reported. Both compounds 1 and 8 showed greater than 99% virus inhibition.

A new 9-nor-atractylodin from Atractylodes lancea and the antibacterial activity of the atractylodin derivatives

A new compound, namely, 9-nor-atractylodin (1) and one known atractylodin (2) were isolated from the rhizomes of Atractylodes lancea. The structural modifications of atractylodin were carried out and a series of atractylodin derivatives (3-10) were obtain

Total synthesis of 1-(Z)-atractylodinol

The total synthesis of 1-(Z)-atractylodinol, a natural polyacetylenic alcohol with several biological activities, has been achieved using a newly developed telluride synthon and a novel use for the Negishi type coupling reaction employing vinyl tellurides.