61655-69-4Relevant academic research and scientific papers
NOVEL COMPOUNDS WITH A 3A-AZABICYCLO [4.1.0] HEPTANE CORE ACTING ON OREXIN RECEPTORS
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Page/Page column 46, (2012/07/14)
This invention relates to azabicyclo[4.1.0]hept-4-yl derivatives and their use as pharmaceuticals.
Piperazinylpyrazines with central serotoninmimetic activity.
Lumma et al.
, p. 536,538 (2007/10/04)
A series of 2-(1-piperazinyl)pyrazines was synthesized and evaluated for central serotonin-like activity. The most interesting member of the series, 6-chloro-2(1-piperazinyl)pyrazine (3a), had pharmacological properties characteristic of potent central serotoninmimetic activity and only weak peripheral serotoninmimetic action. Structural similarities between 3a and serotonin are discussed.
