61655-71-8Relevant academic research and scientific papers
Piperazinylpyrazines
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, (2008/06/13)
Compounds of the formula: STR1 and their N-oxides and acid-addition salts are disclosed having pharmacological activity as anorexic agents.
Piperazinylpyrazines with central serotoninmimetic activity.
Lumma et al.
, p. 536,538 (2007/10/04)
A series of 2-(1-piperazinyl)pyrazines was synthesized and evaluated for central serotonin-like activity. The most interesting member of the series, 6-chloro-2(1-piperazinyl)pyrazine (3a), had pharmacological properties characteristic of potent central serotoninmimetic activity and only weak peripheral serotoninmimetic action. Structural similarities between 3a and serotonin are discussed.
