61655-74-1Relevant academic research and scientific papers
ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
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Paragraph 00523, (2013/10/08)
Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
Piperazinylpyrazines with central serotoninmimetic activity.
Lumma et al.
, p. 536,538 (2007/10/04)
A series of 2-(1-piperazinyl)pyrazines was synthesized and evaluated for central serotonin-like activity. The most interesting member of the series, 6-chloro-2(1-piperazinyl)pyrazine (3a), had pharmacological properties characteristic of potent central serotoninmimetic activity and only weak peripheral serotoninmimetic action. Structural similarities between 3a and serotonin are discussed.
