61656-43-7Relevant academic research and scientific papers
Synthesis and biological evaluation of fluoro-substituted spiro-isoxazolines as potential anti-viral and anti-cancer agents
Boone, Sarah,Das, Prasanta,Hamme, Ashton T.,Mitra, Dipanwita,Raucher, Drazen,Tandon, Ritesh,Turner, Lindsay
, p. 30223 - 30237 (2020/09/03)
Electrophilic fluorine-mediated dearomative spirocyclization has been developed to synthesize a range of fluoro-substituted spiro-isoxazoline ethers and lactones. The in vitro biological assays of synthesized compounds were probed for anti-viral activity
Larvicidal isoxazoles: Synthesis and their effective susceptibility towards Aedes aegypti larvae
Da Silva-Alves, Diana C.B.,Dos Anjos, Janaina V.,Cavalcante, Nery N.M.,Santos, Geanne K.N.,Navarro, Daniela M.Do A.F.,Srivastava, Rajendra M.
supporting information, p. 940 - 947 (2013/03/14)
Twenty 3,5-disubstituted isoxazoles have been synthesized and tested against fourth instar Aedes aegypti larvae. In the synthesis of title compounds, modifications have been made in the C-5 side-chain with a view to test their larvicidal activity. These i
Oxonium ion-mediated synthesis of 4-substituted spiro-isoxazolines
McClendon, Eric,Omollo, Ann O.,Valente, Edward J.,Hamme II, Ashton T.
body text, p. 533 - 535 (2009/04/14)
The stereoselective synthesis of 4-bromo-spiro-isoxazolines was achieved in one step through the bromination of various isoxazoles that contain a pendant alcohol or carboxylic acid functional group. Isoxazole bromination leads to a bromonium ion intermedi
