61667-89-8Relevant academic research and scientific papers
Oxidative Dealkylation of 4-Substituted N,N-Dialkylanilines with Molecular Oxygen in the Presence of Acetic Anhydride Promoted by Cobalt(II) or Copper(I) Chloride
Murata, Satoru,Suzuki, Kaoru,Tamatani, Akira,Miura, Masahiro,Nomura, Masakatsu
, p. 1387 - 1392 (2007/10/02)
The reaction of 4-substituted N,N-dimethylanilines 1a-d with acetic anhydride 5 proceeded efficiently in the presence of a catalytic amount of cobalt(II) or copper(I) chloride under oxygen to give the corresponding N-methylacetanilides 2a-d along with N-methylformanilides 3a-d.The reaction of N-alkyl-N-methyl-p-toluidines 1f-h with cobalt chloride revealed that the order of reactivity of the N-substituents follows the sequence allyl > benzyl >/= methyl > ethyl, while in the case of copper chloride the order was benzyl > allyl > methyl > ethyl.Aldehydes 18a-e and phenylglyoxylic acid derivatives 18f and 18g were obtained in fair to good yield from the reaction of n-substituted N-ethyl-p-toluidines 17a-g.
Cobalt(II) Chloride Catalyzed Oxidation of 4-Substituted N,N-Dialkylanilines with Molecular Oxygen in the Presence of Acetic Anhydride
Murata, Satoru,Tamatani, Akira,Suzuki, Kaoru,Miura, Masahiro,Nomura, Masakatsu
, p. 757 - 760 (2007/10/02)
The oxidation of 4-substituted N,N-dialkylanilines with molecular oxygen using a catalytic amount of cobalt(II) chloride efficiently proceeds in the presence of acetic anhydride to give N-alkylacetanilides in good yields along with N-alkylformanilides.
DIRECT DIACYLATION OF SCHIFF BASES
Vasapollo, Giuseppe,Alper, Howard
, p. 5113 - 5116 (2007/10/02)
A novel diacylation of Schiff bases occurs using catalytic quantities of cobalt carbonyl and phase transfer catalysis conditions.
