616872-66-3Relevant academic research and scientific papers
Synthesis and anti-inflammatory activity of 5-(6-methyl-2-substituted 4-pyrimidinyloxymethyl)-1,3,4-oxadiazole-2-thiones and their 3-morpholinomethyl derivatives
Jakubkiene, Virginija,Burbuliene, Milda Malvina,Mekuskiene, Giedrute,Udrenaite, Emilija,Gaidelis, Povilas,Vainilavicius, Povilas
, p. 323 - 328 (2007/10/03)
The synthesis of 5-(6-methyl-2-substituted 4-pyrimidinyloxymethyl)-2,3-dihydro-1,3,4-oxadiazole-2-thiones and their 3-morpholinomethyl derivatives and the results of anti-inflammatory activity in vivo are described. Most of the tested compounds exhibited anti-inflammatory activity and some of them were more active than acetylsalicylic acid.
