616895-65-9

Basic information

• Product Name: 6-hydroxy-2-ethyl-2H-pyran-3(6H)-one
• CAS NO: 616895-65-9
• Molecular Weight: 142.155
• Mol File: 616895-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-hydroxy-2-ethyl-2H-pyran-3(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxy-2-ethyl-2H-pyran-3(6H)-one(616895-65-9)
• EPA Substance Registry System: 6-hydroxy-2-ethyl-2H-pyran-3(6H)-one(616895-65-9)

Safety Data

• Hazardous Substances Data: 616895-65-9(Hazardous Substances Data)

Upstream product

• 4208-61-1 ethylfurfuryl alcohol 

Relevant articles and documents

Chloroperoxidase-Catalyzed Achmatowicz Rearrangements

Chloroperoxidase from Caldariomyces fumago catalyzes the selective oxidation of furfuryl alcohols in an Achmatowicz-type ring expansion. In combination with glucose oxidase as oxygen-activating biocatalyst, a purely enzymatic, aerobic protocol for the synthesis of 6-hydroxypyranone building blocks is obtained. Thanks to an only modest stereochemical bias of the oxygenating heme protein, optically active alcohols of either configuration are converted without a significant mismatch opening up opportunities for enantioselective multienzymatic cascades. Balancing the oxidase-driven aerobic activation, extended enzyme half-lives and productive conversion of poorly soluble and slowly reacting substrates can be achieved with high yields of the six-membered O-heterocycles.