61699-16-9

Upstream product

• 3316-24-3 1-methoxy-2-((E)-2-nitrovinyl)benzene 
• 108-94-1 cyclohexanone 
• 15241-32-4 1-methoxy-2-(2-nitrovinyl)benzene 

Relevant academic research and scientific papers

Synthesis of a New N-Diaminophosphoryl-N'-[(2S)-2-pyrrolidinylmethyl]thiourea as a Chiral Organocatalyst for the Stereoselective Michael Addition of Cyclohexanone to Nitrostyrenes and Chalcones – Application in Cascade Processes for the Synthesis of Polyc

A highly diastereoselective and enantioselective Michael addition of enolizable ketones such as cyclohexanone and acetophenone to a variety of substituted trans-?-nitrostyrenes and chalcones was catalyzed by a novel chiral and unsymmetrical thiourea as or

Chiral Imidazolium Ionic Liquids Derived from (S)-Prolinamine as Organocatalysts in the Asymmetric Michael Reaction and Michael-Aldol Cascade Reaction under Solvent-Free Conditions

The synthesis of three new chiral imidazolium ionic liquids (prepared by the combination of one new chiral organic cation with different anions) and their application in the enantioselective Michael reaction between cyclohexanone and substituted nitrostyr

Novel thiourea-amine bifunctional catalysts for asymmetric conjugate addition of ketones/aldehydes to nitroalkenes: Rational structural combination for high catalytic efficiency

A series of thiourea-amine bifunctional catalysts have been developed by a rational combination of prolines with cinchona alkaloids, which are connected by a thiourea motif. The catalyst 3a, prepared from l-proline and cinchonidine, was found to be a high

l-Prolinol as a highly enantioselective catalyst for Michael addition of cyclohexanone to nitroolefins

Though many chiral amines such as l-proline and its derivatives have proven to be versatile catalysts in many reactions, l-prolinol was seldom used as organocatalyst for reactions. Herein, we report the first l-prolinol catalyzed asymmetric Michael additi

New pyrrolidine-triazole-based C2 symmetric organocatalysts and their utility in the asymmetric Michael reaction of β-nitrostyrenes and the synthesis of nitrochromenes

The synthesis of new C2 symmetric bis(pyrrolidine-triazole)-based organocatalysts and their utility in the asymmetric Michael reaction of β-nitrostyrenes with very high diastereo- and enantioselectivity in water without any additives is reporte

Synthesis of a new organocatalyst for Michael reactions

A new, easily tunable organocatalyst has been synthesized and applied in the Michael reaction of cyclohexanones to nitrostyrenes.

Organocatalysts wrapped around by poly(ethylene glycol)s (PEGs): A unique host-guest system for asymmetric Michael addition reactions

Asymmetric Michael addition reactions of unmodified ketones to nitroalkenes were performed in PEGs catalyzed by novel pyrrolidinyl-thioimidazolium salts to give products in up to 97% yield and 99% enantioselectivity; ESI mass spectrometric detection for t

Highly enantioselective Michael additions in water catalyzed by a PS-supported pyrrolidine

The development of a highly efficient, polymer-supported organocatalyst for the Michael addition of ketones to nitroolefins is described. A 1,2,3-triazole ring, constructed through a click 1,3-cycloaddition, plays the double role of grafting the chiral pyrrolidine monomer onto the polystyrene backbone and of providing a structural element, complementary to pyrrolidine, key to high catalytic activity and enantioselectivity. Optimal operation in water and full recyclability make the triazole linker attractive for the immobilization of organocatalysts.