61702-03-2

Usage

Type of compound

Heterocyclic compound

Structure

Contains two isoindoline rings

Functional groups

Each isoindoline ring is functionalized with a 6-methylpyridin-2-yl moiety

Potential applications

Organic synthesis, chemical research, and pharmaceuticals

Use as a building block

Synthesis of more complex organic molecules

Role in drug development

Key component in the development of new drug candidates

Unique chemical structure

Valuable tool for researchers and chemists

Areas of science and technology

Diverse fields, including organic synthesis, chemical research, and pharmaceuticals

Upstream product

• 1824-81-3 2-Amino-6-methylpyridine 
• 91-15-6 phthalonitrile 

Relevant academic research and scientific papers

Synthesis, characterization, and electrocatalytic activity of bis(pyridylimino)isoindoline Cu(ii) and Ni(ii) complexes

Two NNN pincer complexes of Cu(ii) and Ni(ii) with BPIMe- [BPIMe- = 1,3-bis((6-methylpyridin-2-yl)imino)isoindolin-2-ide] have been prepared and characterized structurally, spectroscopically, and electrochemically. The single crystal structures of the two complexes confirmed their distorted trigonal bipyramidal geometry attained by three equatorial N-Atoms from the ligand and two axially positioned water molecules to give [Cu(BPIMe)(H2O)2]ClO4 and [Ni(BPIMe)(H2O)2]ClO4. Electrochemical studies of Cu(ii) and Ni(ii) complexes have been performed in acetonitrile to identify metal-based and ligand-based redox activity. When subjected to a saturated CO2 atmosphere, both complexes displayed catalytic activity for the reduction of CO2 with the Cu(ii) complex displaying higher activity than the Ni(ii) analogue. However, both complexes were shown to decompose into catalytically active heterogeneous materials on the electrode surface over extended reductive electrolysis periods. Surface analysis of these materials using energy dispersive spectroscopy as well as their physical appearance suggests the reductive deposition of copper and nickel metal on the electrode surface. Electrocatalysis and decomposition are proposed to be triggered by ligand reduction, where complex stability is believed to be tied to fluxional ligand coordination in the reduced state.

Copper complexes of polyfunctional phthalazines. Mononuclear and polynuclear derivatives

Mononuclear, binuclear, and trinuclear copper(II) complexes of the tetradentate ligands 1,4-di(2'-pyridyl) aminophthalazine (PAP) and 1,4-di(4'-methyl-2'-pyridyl) aminophthalazine (PAP4Me) and binuclear complexes of the tetradentate ligand 1,4-di(6'-methyl-2'-pyridyl) aminophthalazine (PAP6Me) are reported.In a series of binuclear carboxylate derivatives carboxylate bridges exist between copper centres in all cases and in some cases oxygen bridges (hydroxide or methoxide) are indicated.In all other polynuclear derivatives hydroxide bridges are anticipated on the basis of analytical, spectral and magnetic data.The ligands exist as anionic groups in some binuclear carboxylate derivatives while in the other polynuclear systems neutral ligands are found.In reactions in aqueous solution protonated mononuclear derivatives are obtained for both PAP and PAP4Me in cases where solutions of the metal salts are inherently acidic, followed by polynuclear, neutral ligand complexes which form when the pH increases.Mononuclear protonated complexes are not obtained with PAP6Me, where steric factors may prevent the formation of such derivatives.Low magnetic moments (1.1-1.5 BM) are observed for most hydroxy bridged complexes while even lower values (NO3 indicates a triple bridged binuclear structure including a bidentate nitrate bridge and a hydroxide bridge with an oxygen bridge angle of 115.2 deg.