61703-39-7

Basic information

• Product Name: L-1-CBZ-PIPECOLINAMIDE
• Synonyms: L-1-CBZ-PIPECOLINAMIDE ;(S)-2-Carbamoyl-piperidine-1-carboxylic acid benzyl ester;S-1-Cbz-Pipecolinamide;benzyl (2S)-2-carbaMoylpiperidine-1-carboxylate;(S)-2-(Aminocarbonyl)-1-piperidinecarboxylic acid phenylmethyl ester;Benzyl (2S)-2-(aminocarbonyl)piperidine-1-carboxylate;(S)-1-Cbz-2-piperidinecarboxaMide;(S)-Benzyl 2-carbamoylpiperidine-1-carboxylate
• CAS NO: 61703-39-7
• Molecular Formula: C₁₄H₁₈N₂O₃
• Molecular Weight: 262.30432
• Mol File: 61703-39-7.mol

Chemical Properties

• Boiling Point: 475.5 °C at 760 mmHg
• Flash Point: 241.4 °C
• Appearance: /
• Density: 1.224
• Vapor Pressure: 3.3E-09mmHg at 25°C
• Refractive Index: 1.568
• Storage Temp.: 2-8°C
• CAS DataBase Reference: L-1-CBZ-PIPECOLINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: L-1-CBZ-PIPECOLINAMIDE(61703-39-7)
• EPA Substance Registry System: L-1-CBZ-PIPECOLINAMIDE(61703-39-7)

Safety Data

• Hazardous Substances Data: 61703-39-7(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
L-1-Cbz-pipecolinamide is used as a key intermediate in the synthesis of complex organic molecules. Its N-protected structure facilitates the formation of desired products while preventing unwanted side reactions, making it a valuable component in the construction of intricate chemical frameworks.
Used in Pharmaceutical Processes:
L-1-Cbz-pipecolinamide is employed as a building block in the development of new pharmaceutical compounds. Its chiral nature allows for the creation of enantiomerically pure drugs, which is crucial for ensuring the desired therapeutic effects and minimizing potential side effects. L-1-Cbz-pipecolinamide's versatility in chemical reactions enables the synthesis of a wide range of bioactive molecules with potential applications in various therapeutic areas.

InChI:InChI=1/C14H18N2O3/c15-13(17)12-8-4-5-9-16(12)14(18)19-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10H2,(H2,15,17)/t12-/m0/s1

Upstream product

• 28697-11-2 (S)-1-(carbobenzyloxy)-2-piperidinecarboxylic acid 

Downstream Products

• 1154871-02-9 benzyl (2S)-2-(aminomethyl)piperidine-1-carboxylate 

Relevant articles and documents

PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinaldamage, skin senescence and UV-induced skin damage, and as chemo-or radiosensitizers for cancer treatment.