61714-25-8 Usage
Chemical Properties
Off-White Crystalline Solid
Biological Activity
Calmodulin antagonist (inhibits Ca 2+ -calmodulin dependent PDE with an IC 50 of 240 μ M).
Check Digit Verification of cas no
The CAS Registry Mumber 61714-25-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,7,1 and 4 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61714-25:
(7*6)+(6*1)+(5*7)+(4*1)+(3*4)+(2*2)+(1*5)=108
108 % 10 = 8
So 61714-25-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O2S/c17-12-5-1-2-6-13-18-21(19,20)16-11-7-9-14-8-3-4-10-15(14)16/h3-4,7-11,18H,1-2,5-6,12-13,17H2/p+1
61714-25-8Relevant articles and documents
Treatment of amyloidosis associated with Alzheimer disease using modulators of protein phosphorylation
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, (2008/06/13)
A method of regulating phosphorylation of proteins involved in controlling processing or function of key proteins found in intracellular neurofibrillary tangles and extracellular amyloid plaques associated with Alzheimer disease comprising introducing an effective amount of a kinase modulator or phosphatase modulator, the modulator capable of increasing or decreasing the rate of proteolytic processing, or modulating the function, of said key proteins.
