61719-59-3Relevant academic research and scientific papers
1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND
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Page/Page column 82-83, (2008/06/13)
The objective of this invention is to provide novel compounds that show excellent DPPIV-inhibiting activity. The present invention provides compounds represented by the general formula (I), salts thereof, or hydrates thereof, [wherein,T1 stands for a monocyclic or bicyclic 4 to 12-membered heterocycle having 1 or 2 nitrogen atoms in the ring, which may have substituents; in formula (I), the following formula represents a double bond or a single bond; X3 denotes an oxygen atom or a sulfur atom; X1 denotes a C2-6 alkynyl group which may have substituents; Z1 denotes a nitrogen atom or the formula -CR3=; Z2 and Z3 each independently denote a nitrogen atom, the formula -CR1=, a carbonyl group, or the formula -NR2-; R1, R2, R3, and X2 each independently denote a C1-6 alkyl group which may have substituents, and such].
SYNTHESIS AND PROPERTIES OF 4-HALOIMIDAZOPYRIDIN-2-ONES
Yutilov, Yu.M.,Svertilova, I.A.
, p. 923 - 927 (2007/10/02)
The nitro group in 4-nitroimidazopyridin-2-ones is rather labile and may be reploaced upon heating with hydrohalic acids to give the corresponding 4-halides.A methyl group at N(3) leads to a sharp increase in the lability of the nitro gr
